A Special Theme Issue of the Philosophical Transactions of the Royal Society B, ‘One Health for a Changing World: zoonoses, ecosystems and human well-being’, showcases work produced by the Drivers of Disease Consortium. The Open Access publication is co-edited by Ian Scoones, Andrew Cunningham and James Wood.
Effects of flood irrigation on the risk of selected zoonotic pathogens in an arid and semi-arid area in the eastern Kenya, was published in PLoS ONE, authored by Bernard Bett, Mohammed Y. Said, Rosemary Sang, Salome Bukachi, Salome Wanyoike, Shem C. Kifugo, Fredrick Otieno, Enoch Ontiri, Ian Njeru, Johanna Lindahl and Delia Grace.
‘Effects of climate change on the occurrence and distribution of livestock diseases‘ was published in Preventive Veterinary Medicine, authored by Bernard B, Kiunga P, Gachohi , Sindato C, Mbotha D, Robinson T, Lindahl J, and Delia G.
‘A multi-host agent-based model for a zoonotic, vector-borne disease. A case study on trypanosomiasis in Eastern Province, Zambia‘, authored by Simon Alderton, Ewan Macleod, Neil Anderson, Kathrin Schaten, Joanna Kuleszo, Martin Simuunza, Susan Welburn and Peter Atkinson, has been published in in PLoS Neglected Tropical Diseases.
‘Effects of irrigation and rainfall on the population dynamics of Rift Valley fever and other arbovirus mosquito vectors in the epidemic-prone Tana River County, Kenya’, authored by Sang R, Lutomiah J, Said M, Makio A, Koka H, Koskei E, Nyunja A, Owaka S, Matoke-Muhia D, Bukachi S, Lindahl J, Grace D and Bett B, was published in the Journal of Medical Entomology.
‘Spatial distribution and trypanosome infection of tsetse flies in the sleeping sickness focus of Zimbabwe in Hurungwe District’, authored by William Shereni, Neil Anderson, Learnmore, Nyakupinda, Giuliano Cecchi, has been published in Parasites & Vectors.
‘Modelling the spatial-temporal distribution of tsetse (Glossina pallidipes) as a function of topography and vegetation greenness in the Zambezi Valley of Zimbabwe’, authored by Farai Matawa, Amon Murwira, Fadzai Zengeya and Peter Atkinson, has been published in Applied Geography.
‘Ecological monitoring and health research in Luambe National Park, Zambia: generation of baseline data layers‘, authored by Neil Anderson, Paul Bessell, Joseph Mubanga, Robert Thomas, Mark Eisler, Eric Fèvre and Susan Welburn, has been published in EcoHealth.
A paper, ‘Environmental-mechanistic modelling of the impact of global change on human zoonotic disease emergence: a case study of Lassa fever’, detailing a study testing a new model that predicts outbreaks of zoonoses based on changes in climate, population growth and land use, has been published in Methods in Ecology and Evolution. The authors are Dave Redding, Lina Moses, Andrew Cunningham, James Wood and Kate Jones.
‘Zoonotic diseases: who gets sick, and why? Explorations from Africa’, explores the social dynamics of disease exposure through the five Drivers of Disease case studies and proposes a framework to assist the understanding of and response to zoonoses within a One Health approach. It is published in Critical Public Health and authored by Consortium partners Vupenyu Dzingirai, Bernard Bett, Sally Bukachi, Elaine Lawson, Lindiwe Mangwanya, Ian Scoones, Linda Waldman, Annie Wilkinson, Melissa Leach and Tom Winnebah.
‘Moving interdisciplinary science forward: integrating participatory modelling with mathematical modelling of zoonotic disease in Africa’ by Catherine Grant, Giovanni Lo Iacono, Vupenyu Dzingirai, Bernard Bett, Thomas R. A. Winnebah and Peter M. Atkinson has been published in Infectious Diseases of Poverty.
One Health: Science, politics and zoonotic disease in Africa, edited by Kevin Bardosh, has been published. This book offers a political economy analysis of zoonoses research and policy, with chapters from Drivers of Disease researchers and using Drivers of Disease case studies.
Caroline M Ng’ang’a, Salome Bukachi and Bernard Bett have co-authored ‘Lay perceptions of risk factors for Rift Valley fever in a pastoral community in northeastern Kenya‘ published in BMC Public Health.
Kate Jones, together with Liam Brierley, Maarten J. Vonhof , Kevin J. Olival, Peter Daszak, has authored ‘Quantifying Global Drivers of Zoonotic Bat Viruses: A Process-Based Perspective’, published in The American Naturalist.
Catherine Grant, Neil Anderson and Noreen Machila co-authored a paper, ‘Stakeholder narratives on trypanosomiasis, their effect on policy and the scope for One Health’, in PLoS Neglected Tropical Diseases.
‘Exploiting human resource requirements to infer human movement patterns for use in modelling disease transmission systems: an example from Eastern Province, Zambia‘ authored by Consortium partners Simon Alderton, Jason Noble, Kathrin Schaten, Sue Welburn and Peter Atkinson was published in PLoS ONE.
The Drivers of Disease Sierra Leone environment and land-use team, comprising Alie Kamara, Bashiru Koroma and Alhagi Gogra, published ‘Seasonal changes in vegetation and land use in Lassa-fever-prone areas (Kenema and Kailahun Districts) in Eastern Sierra Leone’ in Natural Resources.
Delia Grace and Victor Galaz sat on the 2015 Lancet Commission on Health and Climate Change which culminated in the publication of Health and climate change: policy responses to protect public health. This maps out the impacts of climate change, and the necessary policy responses, to ensure the highest attainable standards of health for populations worldwide
‘Sleeping sickness and its relationship with development and biodiversity conservation in the Luangwa Valley, Zambia‘, by Consortium partners Neil Anderson, Joseph Mubanga (now deceased), Noreen Machila, Peter Atkinson, Vupenyu Dzingerai and Susan Welburn was published in Parasites & Vectors.
Lassa fever: The politics of an emerging disease and the scope for One Health, by Annie Wilkinson; The political economy of One Health research and policy, by Victor Galaz, Melissa Leach, Ian Scoones and Christian Stein; and Rift Valley fever in Kenya: Policies to prepare and respond, by Erik Millstone, Hannington Odame and Oscar Okumu, have been published, bringing to completion the Drivers of Disease political economy of knowledge and policy theme working paper series.
Responding to uncertainty: Bats and the construction of disease risk in Ghana, by Linda Waldman, Audrey Gadzekpo and Hayley MacGregor, published in the Drivers of Disease political economy of knowledge and policy theme working paper series.
Gianni Lo Iacono, Andrew Cunningham, Donald Grant, Melissa Leach, Lina Moses and James Wood are among the co-authors of ‘Using Modelling to Disentangle the Relative Contributions of Zoonotic and Anthroponotic Transmission: The Case of Lassa Fever’ published in PLOS Neglected Tropical Diseases.
Two new working papers have been published under the political economy of knowledge and policy theme of the Drivers of Disease consortium. Towards One Health? Evolution of international collaboration networks on Nipah virus research from 1999-2011 is by Sophie Valeix. Politics of knowledge: Whose knowledge matters in trypanosomiasis policy making in Zambia is by Catherine Grant.
Delia Grace and Bernard Bett, both of ILRI, have co-authored a chapter on zoonotic diseases and their drivers in Africa in a new book, Climate Change and Global Health, published by CABI.
Sue Welburn is co-author of ‘Neglected Zoonotic Diseases – The long and winding road to advocacy‘, published in PLOS Neglected Tropical Disease.
Sue Welburn is co-author of ‘One Health: Past Successes and Future Challenges in Three African Contexts‘ published in PLOS Neglected Tropical Diseases. The article explores the practical implementation of One Health policies by considering how the One Health approach has been applied in Uganda, Nigeria and Tanzania.
The Politics of Trypanosomiasis Control in Africa by Ian Scoones has been been published by The STEPS Centre as a Working Paper. It explores the scientific and policy debates surrounding the control of trypanosomiasis, particularly in the Drivers of Disease case study countries Zambia and Zimbabwe.
James Wood, Andrew Cunningham and Richard Suu-Ire are among the co-authors of a study published in Nature Communications which found that that 42 per cent of the ‘gregarious’ straw-coloured fruit bat (Eidolon helvum) in Africa are infected with henipaviruses- with consequent important public health implications. An article on BBC News outlines the study.
The Drivers of Disease Consortium has published five research updates, one for each of its case study countries. Each update outlines the background to the case study disease being investigated, describes the key questions the research team is exploring, along with some of the knowns and unknowns, and gives a brief outline of the research methodologies being followed.
The updates are available for download in PDF format:
- Situation Analysis Research Update Ghana
- Situation Analysis Research Update Kenya
- Situation Analysis Research Update Sierra Leone
- Situation Analysis Research Update Zambia
- Situation Analysis Research Update Zimbabwe
Melissa Leach and Ian Scoones have co-authored ‘The social and political lives of zoonotic disease models: Narratives, science and policy‘, published in Social Science & Medicine, which proposes multiple multidisciplinary models and modelling aproaches to understand the scientific and policy challenges presented by zoonotic disease threats.
Partners in the Drivers of Disease Consortium have co-written a four-page IDS Rapid Response Briefing entitled Zoonoses – From Panic to Planning which proposes seven recommendations to realign policy making for disease control and eradication to embrace a One Health approach.
Consortium infectious disease epidemiologist James Wood and mathematical modeller Gianni Lo Iacono have co-authored ‘How does the ecology of Culicoides biting midges influence the risk of an epidemic of African Horse Sickness?‘ published in the Journal of Equine Veterinary Science. The findings are relevant to the Drivers of Disease case study of Rift Valley Fever in Kenya.
Drivers of Disease partner Sue Welburn has co-authored ‘Trypanosome Diversity in Wildlife Species from the Serengeti and Luangwa Valley Ecosystems’, published in PLOS Neglected Tropical Diseases. The paper reports research investigating the presence in wildlife of the microscopic parasites that cause the disease trypanosomiasis in livestock and humans, and describes how previously unclassified variants of Typanosoma vivax, which cause disease in cattle, were found in giraffe and waterbuck. It considers how traditional systems of classifying trypanosomes are now being challenged by new molecular data.
A special issue of Philosophical Transactions B of the Royal Society, with the theme ‘Disease invasion: impacts on biodiversity and human health’, has been co-compiled and co-edited by Drivers of Disease partner Andrew Cunningham. The journal features a research article, ‘A framework for the study of zoonotic disease emergence and its drivers: a spillover of bat pathogens as a case study’, co-authored by, among others, Drivers of Disease partners James Wood, Melissa Leach, Yaa Ntiamoa-Baidu, Richard Suu-Ire and Andrew Cunningham. In it, the authors propose a novel framework for the holistic and interdisciplinary investigation of zoonotic disease emergence and its drivers.
Drivers of Disease partner Delia Grace, a veterinary epidemiologist at ILRI, has edited a special supplement of the journal Tropical Animal Health and Production, on assessing and managing urban zoonoses and food-borne diseases in Nairobi and Ibadan. The supplement comprises a set of 11 papers setting out how ecohealth approaches can make a difference to city health. Read an ILRI News article on the research, and a related Guardian Poverty Matters blog, How to stop zoonoses spreading – don’t keep chickens under the bed‘, in which Delia is interviewed.
A major mapping study co-authored by Drivers of Disease partner Delia Grace identifies 13 zoonotic diseases which together cause 2.4 billion cases of human illness and 2.2 million deaths each year, mainly among the world’s poorest people. Read Mapping of Poverty and Likely Zoonoses Hotposts, (ILRI) by D. Grace et al, on the CGIAR website, or a report on the study on the Nature website.
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